Sliding Mechanism for Actin Myosin System

نویسندگان

  • Bao-quan Ai
  • Xian-ju Wang
  • Guo-tao Liu
  • Liang-gang Liu
  • M. Nakano
  • H. Matsuura
چکیده

Based on the Stochastic Inclined Rods Model (SIRM) proposed by H. Matsuura and M. Nakano, we study the microscopic motion of actin myosin system including the motion of the G-actin. Our model is composed of an inclined spring (rod), a myosin head, a myosin filament and G-actins. We discuss the stochastic resonance between the myosin head and random noise. The results of calculation show that the model can convert the random motion to one directional motion, and the myosin head works as a resonator of random noise which absorbs the energy through the stochastic resonance. The intermolecular potential between the myosin head and G-actin and the inclined rod play a key role for the muscle’s motion. The energy consumed by the motor is directly supplied from the surroundings (i.e., the thermal motions of water molecules).

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تاریخ انتشار 2003